New formulation and approach for mucoadhesive buccal film of rizatriptan benzoate
نویسندگان
چکیده
منابع مشابه
New formulation and approach for mucoadhesive buccal film of rizatriptan benzoate
Mucoadhesive buccal film is developed as a promising dosage form, which has prominent advantages because of drug delivery through buccal mucosa. New formulation of buccal films containing rizatriptan benzoate (RB) was prepared by solvent casting method using various concentrations of hydroxypropyl methylcellulose (HPMC K4M), polyvinyl alcohol (PVA), polyethylene oxide (PEO), glycerol, stevia, a...
متن کاملFormulation and Evaluation of Rizatriptan Benzoate Mouth Disintegrating Tablets
The present investigation deals with development of mouth disintegrating tablets of rizatriptan benzoate to produce the intended benefits. Mouth disintegrating tablets of rizatriptan benzoate were prepared using superdisintegrants crospovidone, carboxymethylcellulose calcium, Indion 414 and Indion 234 using the direct compression method. The tablets prepared were evaluated for thickness, unifor...
متن کاملPreparation and pharmaceutical evaluation of Mucoadhesive Buccal film extracts of petroselinum for pharyngitis symptoms
Background: Recently, the mucosa has attracted attention due to its large arteries and high permeability for drug delivery. Due to the anti-inflammatory effect of parsley and easy access to this plant in Iran and the fact that the adhesive mucosa film is a new method with high performance and efficiency of drug transfer, this study was done to evaluate the effect of this plant on the pharyngiti...
متن کاملDevelopment of Abelmoschus esculentus (Okra)-Based Mucoadhesive Gel for Nasal Delivery of Rizatriptan Benzoate
Purpose: To develop a safe mucoadhesive gel for nasal drug delivery using okra polysaccharide. Methods: Rizatriptan benzoate nasal gel was developed using natural polysaccharide obtained from the Abelmoschus esculentus. The gel formulation was characterized for pH, viscosity, mucoadhesion, and in vitro permeation. Permeation parameters obtained include drug flux (j), permeation coefficient (kP)...
متن کاملFormulation and Evaluation of Mucoadhesive Buccal Films of Enalapril Maleate
Enalapril maleate is used in the treatment of hypertension and angina pectoris. It shows low bioavailability due to high hepatic first pass metabolism. Hence the present work was undertaken to formulate mucoadhesive buccal films of enalapril maleate with an objective to improve therapeutic efficacy, patient compliance and the bioavailability. In the present study ten formulations of mucoadhesiv...
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ژورنال
عنوان ژورنال: Progress in Biomaterials
سال: 2017
ISSN: 2194-0509,2194-0517
DOI: 10.1007/s40204-017-0077-7